Radioimmunoassay (RIA) is an immunoassay that uses radiolabelled molecules in a stepwise formation of immune complexes. RIA is an extremely sensitive and specific in vitro assay technique used to measure concentrations of substances in body fluids such as blood and saliva. Specialised gamma counters are necessary to measure the reactivity of the sample and analyse the results. Special precautions and licensing are required due to the presence of low level radioactive substances (typically the iodine isotype I125), however RIA remains a popular technology due to the high sensitivity and specificity.

Oxford Biosystems has a wide range of RIA kits available from Diasource, IBL and Cisbio.

Diasource is part of the BioVendor Group and is one of the few remaining independent RIA manufacturers worldwide, offering an a wide range of products and specialising in Endocrinology.

Please use the search facility (top right) to find your product of interest or contact us directly to discuss your requirements.

Enzyme linked immunosorbent assay (ELISA) is the most widely used type of immunoassay. An enzyme-labelled specific antibody to the analyte of interest, reacts with a substrate to produce a reaction that is detected and quantified

Oxford Biosystems has an extensive range of ELISA kits available for clinical and research use, from a number of international manufacturers including BioVendor, Diasource and TestLine, all companies within the BioVendor Group.

• Infectious diseases
• Endocrinology
• Immunology
• Vitamin D
• Cardiovascular disease
• Bone metabolism
• Neurodegenerative diseases

Please use the search facility (top right) to find your product of interest or contact us directly to discuss your requirements.

ELISA is ideal for screening large numbers of samples and is easily automatable, with a wide variety of analysers and sample processing instruments available. We have a range of instrumentation including microplate washers and readers, sample processors and fully automated ELISA processing systems. Please contact us to discuss your specific requirements.

First described in 1993, the small regulatory molecules called microRNA or miRNA, have become emerging biomarkers for research in all fields of medical and biological sciences. This new miRNA regulatory domain empowers translational R&D, identifies novel disease biomarkers in biofluids and tissues and develops non-invasive screening and diagnostic tests.

miREIA is a novel, immunoassay-based method of miRNA quantification which involves hybridisation of miRNA isolated from a patient sample to complementary biotinylated DNA oligonucleotide probe. The DNA/RNA hybrids are then captured by a microtiter plate-immobilized monoclonal antibody specific to perfectly matched DNA/miRNA hybrids. The next steps in the assay procedure follow standard ELISA protocols and the assay can be run on common immunoassay equipment. The method is compatible with standard clinical workflow, does not require amplification steps and results are obtained in less than three hours, including miRNA profiling.

BioVendor have a range of miREIA kits available for various research applications. For additional information please contact us directly.